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LOD,LOQ in validation

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LOD,LOQ in validation

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saipraveen7
Can anyone please provide me a link for detailed explanation regrading how to determine Limit of detection and Limit of Quantitation in analytical method validation by HPLC

Re: LOD,LOQ in validation

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tom jupille
Site Admin
You can find the general requirements on page 11 of this document:
http://www.ich.org/fileadmin/Public_Web ... deline.pdf

My preference is the standard error and slope method: viewtopic.php?f=1&t=22835
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
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