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- Posts: 151
- Joined: Sat Feb 13, 2010 9:54 pm
I am looking for some feedback. I was running a Q1 scan the other day and noticed my baseline noise was between 5x10E4 and 1x10E5. This was 10 scans MCA mode, so if I did not run MCA mode the noise would be 1/10th or about 5x10E3 to 1x10E4 let's say.
Oh, and I was in negative ion mode, -4500 volts.
I thought this was a bit high. I have a much older instrument that gives me almost 1/10th this noise. Would this be considered normal on an API 3000?
Mobile phase was 65/35 MeOH/5mM AmAc aq. and I had a split so I was probably spraying in about 40 -50 uL/min, ionspray.
Q1 scan 50 to 500 AMU.
Thanks
Alp
