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end-capped polar-embedded octadecylsilyl column
Posted: Wed Apr 10, 2013 8:20 am
by truongdv
Hello HPLC expert,
Can someone recommend me any HPLC column with:
- stationary phase: end-capped polar-embedded octadecylsilyl amorphous organosilica polymer R (150 x 4.6, 5µm)
- stationary phase: octadecyl vinyl polymer for chromatography R (250 x 4.6,5 µm)
- stationary phase: trimethylsilyl silica gel for chromatography R (250 x 4.6,5 µm)
Thanks,
Truong
Re: end-capped polar-embedded octadecylsilyl column
Posted: Wed Apr 10, 2013 8:35 am
by Gerhard Kratz
Dear Truong,
Polar embedded columns are available from several manufacturers like Waters, Supelco, Phenomenex, Thermo. One example is Symmetry Shield!
Polymer based RP18 materials are available from 3 manufacturers: Agilent (former PolymerLabs column), Hamilton and Tosoh. And maybe several new companies will now popup and claim that they also have such a material.
Your last column request is a C1 material. Please google for that one.
Good luck
Re: end-capped polar-embedded octadecylsilyl column
Posted: Wed Apr 10, 2013 11:04 am
by HPLCaddict
- stationary phase: end-capped polar-embedded octadecylsilyl amorphous organosilica polymer R (150 x 4.6, 5µm)
This asks for "organosilica polymer", so this is no ordinary silica column but a hybride column. Therefore Symmetry Shield is no option. The only columns that fit this description (and I am aware of) are the XBridge Shield and XTerra RP18 (XTerra RP18 is polar-embedded, while XTerra MS18 is not!), both from Waters. The other hybrides that I know (Gemini and Gemini NX from Phenomenex, Triart by YMC) are not available as polar-embedded.
Re: end-capped polar-embedded octadecylsilyl column
Posted: Fri Aug 28, 2020 7:52 am
by cyriljose17
Dear Sir,
Can you please quote reference for the column chemistry of Xterra RP18 columns. would be helpful
Re: end-capped polar-embedded octadecylsilyl column
Posted: Fri Aug 28, 2020 10:13 am
by vmu
end-capped polar-embedded octadecylsilyl amorphous organosilica polymer R
Example: European Pharmacopeia, IMIPRAMINE HYDROCHLORIDE, Related substances ---> EDQM Knowledge Database points at XTerra Shield RP18.
https://extranet.edqm.eu/4DLink1/4DCGI/Web_View/mono/29
octadecyl vinyl polymer for chromatography R
Example: European Pharmacopeia, FORMOTEROL FUMARATE DIHYDRATE, Impurity I ---> EDQM Knowledge Database points at Asahipak ODP-50 or Astec Polymer C 18.
https://extranet.edqm.eu/4DLink1/4DCGI/ ... /mono/1724
trimethylsilyl silica gel for chromatography R
Example: European Pharmacopeia, PAROXETINE HYDROCHLORIDE,
ANHYDROUS, Assay ---> EDQM Knowledge Database points at Zorbax TMS.
https://extranet.edqm.eu/4DLink1/4DCGI/ ... /mono/2283
Upd: oops, it was in 2013.