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- Posts: 33
- Joined: Sat Jan 15, 2011 2:53 am
I have the following question:
1.During intermediation precision validation, do you prefer to evaluate overall RSD% or absolute mean difference%?
2.Would one give a better evaluation than the other? Or does it depends on individual's preference?
My opinion is either way is OK.
I have heard some people do not like overall RSD% because 12 results are not enough to evaluate inter lab RSD%. However I doubt if absolute mean difference% is better. For example, one lab has 99% for all 6 assays and the other lab has 101% for all 6 assays, the absolute difference is 3% and RSD is 2.1%. This can not tell you if one is better than the other. either way is fine.
I'd appreciate your input on this topic.
1.During intermediation precision validation, do you prefer to evaluate overall RSD% or absolute mean difference%?
2.Would one give a better evaluation than the other? Or does it depends on individual's preference?
My opinion is either way is OK.
I have heard some people do not like overall RSD% because 12 results are not enough to evaluate inter lab RSD%. However I doubt if absolute mean difference% is better. For example, one lab has 99% for all 6 assays and the other lab has 101% for all 6 assays, the absolute difference is 3% and RSD is 2.1%. This can not tell you if one is better than the other. either way is fine.
I'd appreciate your input on this topic.
