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Dispersion media for Particle size analysis
Posted: Wed Feb 20, 2013 3:33 am
by vagarwal
Hi just need some suggestions on a suitable dispersion media for particle size analysis of a highly water soluble drug. Solvent has to be Hexane and up. Need a suitable wetting agent to keep my drug dispersed.
Any Ideas!!!
Re: Dispersion media for Particle size analysis
Posted: Wed Feb 20, 2013 2:27 pm
by shepchemalum
For most of my water soluble particle methods, I use 0.2%SPAN-80 in Hexane, seems to work pretty well. Use a small amount of the mixture to wet the sample until it's a slurry, then introduce it into your analyzer filled with the hexane/SPAN mixture.
Re: Dispersion media for Particle size analysis
Posted: Wed Feb 20, 2013 10:27 pm
by vagarwal
thanks for the suggestion will try that...