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Hexane and Agilent 1946d MS

Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.

3 posts Page 1 of 1
I just had a 1946d Agilent MS installed with an 1100 pump system and DAD detector. When I ran a sample through the column with hexane/IPA as the solvent I got a response on the DAD but the MS was quiet, too quiet.

I'm wondering if maybe hexane doesn't work as a solvent for the MS?
Incitor Inc.
"Making renewable fuels a reality"
http://www.incitor.com
It's not a particularly good choice for electrospray, but what's the sample/analyte?
Here's a useful link on hexane in electrospray: http://web.uvic.ca/~mcindoe/42.pdf
It's not a particularly good choice for electrospray, but what's the sample/analyte?
Here's a useful link on hexane in electrospray: http://web.uvic.ca/~mcindoe/42.pdf
The analyte is chloromethyl furfural, ethyl furoate ester, and some other unknown compounds. We had initially decided to use hexane as a "weak" solvent, as our analytes are more on the polar side. Do you have any suggestions for a good nonpolar solvent for electrospray?
Incitor Inc.
"Making renewable fuels a reality"
http://www.incitor.com
3 posts Page 1 of 1

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