Ammonium Formate as mobile phase in LCMSMS

[hts123]

I am trying out a new method called EPA 1694. I wanted to test for acetaminophen in water hence I had to prepare the buffer solution as mobile phase for the LCMSMS.

Ammonium formate is used as part of the buffer solution for mobile phase. Upon running a search on the internet, I found out there are many different kinds of ammonium formate, which includes ammonium formate specifically for mass spectrometry.

Hence I will like to enquire if am I able to use normal reagent grade ammonium formate for this test or must I use mass spectro specific ammonium formate?

Thanks in advance to anyone who have the answer to my question.

[HPLC chemist]

Because you are using an MS detector you must use the MS grade of Ammonium Formate. Ammonium Formate (technical grade) has a lot of impurities.

[hts123]

Thank you @hplc chemist.