How to Fight “Batman” Peaks

[Vlad Orlovsky]

I would appreciate suggestion on the topic. I am trying to develop a method for metal complexes (Pt, Pd, Ru, Rh, Ir) and I constantly observe "Batman" type of peaks for palladium and platinum. How can I shift equlibrium o obtain a better peak? I tried various mobile phase conditions (pH, rations, adding ligand to the mobile phase) but still don't like peak shape. Unfortunately I cannot reveal more since it is something new we are trying to develop.

[JMB]

Low-level cyclodextrin in mobile phase to complex the M ??

JMB

[krickos]

Hi Vlad

Not at work and not for the coming days, so a question that may seem basic but just to be sure:

Some complexes are extremly sensitive/narrow in range (you can check pourbaix diagrams or similar for estimate for most metal complexes), so in theory are you certain that these complexes will actually appear in 100% of your target complex under your analytical conditions?