UPLC grade water or HPLC grade water??

[seamoro]

Im running on UPLC for the last month and ive had serious pressure problems....i finally think its the water we are using. I found this article...... http://www.hplc.hu/PDFs/UHPLC_MobilePhasePrep.pdf. It suggests that even though i using hplc grade water filtered through 0.2um filter that this isnt good enough!! has anybody had experience of this??

[KRRISH8]

I think problem with your column? Switch to new column.

[silmartras]

Usually this filtration is enough. Check the prefilter of the column.