Sulfonate & Disulfonate derivitisation
Posted: Fri Sep 14, 2012 4:14 pm
Hi all,
Me and my colleague have been asked to look into the development of a method for low level detection (<50ppm though ideally <10ppm) of a disulfonate compound MMDS (methylene methane disulfonate).
The compound in question does not absorb at a useful UV wavelength for UV detection and so the method I am using for the determination of MMDS in large concentrations involves an RID. As I am sure you are all aware the RID is not a very sensitive detector and tests I have carried out so have led to an estimated LOD of 0.1% (way above the concentrations my superiors have in mind!).
I was wondering if anyone has any experience with regards to the analysis of sulfonate compounds and could suggest a derivitisation agent I could perhaps try so that UV detection can be employed in place of RID.
As ever any information provided will be very much appreciated.
Kind regards,
James
Me and my colleague have been asked to look into the development of a method for low level detection (<50ppm though ideally <10ppm) of a disulfonate compound MMDS (methylene methane disulfonate).
The compound in question does not absorb at a useful UV wavelength for UV detection and so the method I am using for the determination of MMDS in large concentrations involves an RID. As I am sure you are all aware the RID is not a very sensitive detector and tests I have carried out so have led to an estimated LOD of 0.1% (way above the concentrations my superiors have in mind!).
I was wondering if anyone has any experience with regards to the analysis of sulfonate compounds and could suggest a derivitisation agent I could perhaps try so that UV detection can be employed in place of RID.
As ever any information provided will be very much appreciated.
Kind regards,
James