Midodrine, Oxcarbazepine and Cilostazol [May 31, 2004]
Posted: Tue Aug 24, 2004 10:57 pm
By Himika Varma on Monday, May 31, 2004 - 12:36 am:
Can anyone here provide text / reference to HPLC methods of analysis for Midodrine, Oxcarbazepine and Cilostazol?
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By maris on Monday, May 31, 2004 - 01:23 pm:
Midodrine and Cilostazol monogarphs (including HPLC methods for related substances) can be found in Japanese Pharmacopoeial Codex (JPC) - as I remember for Midodrine only the Japanese version is available.
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By Himika Varma on Tuesday, June 1, 2004 - 01:13 am:
Thanks Maris.
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By Einar Pontén - SeQuant AB on Tuesday, June 1, 2004 - 03:23 pm:
At least Midodrine seems to be a candidate that may be retained by HILIC, in case the pharmacopé method is not sufficient.
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By Anonymous on Tuesday, June 1, 2004 - 03:45 pm:
Did you try any Rp columns or methods? My guess is that midodrine retains very poorly (compare to other two) and obtaining a good isocratic method might be a problem
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By Himika Varma on Wednesday, June 2, 2004 - 04:15 pm:
Thanks guys. Have downloaded the methods and am working on them.
Will let you know if run into trouble again.
Regards.
Can anyone here provide text / reference to HPLC methods of analysis for Midodrine, Oxcarbazepine and Cilostazol?
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By maris on Monday, May 31, 2004 - 01:23 pm:
Midodrine and Cilostazol monogarphs (including HPLC methods for related substances) can be found in Japanese Pharmacopoeial Codex (JPC) - as I remember for Midodrine only the Japanese version is available.
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By Himika Varma on Tuesday, June 1, 2004 - 01:13 am:
Thanks Maris.
-------------------------------------------------------------------------------------------------------
By Einar Pontén - SeQuant AB on Tuesday, June 1, 2004 - 03:23 pm:
At least Midodrine seems to be a candidate that may be retained by HILIC, in case the pharmacopé method is not sufficient.
-------------------------------------------------------------------------------------------------------
By Anonymous on Tuesday, June 1, 2004 - 03:45 pm:
Did you try any Rp columns or methods? My guess is that midodrine retains very poorly (compare to other two) and obtaining a good isocratic method might be a problem
-------------------------------------------------------------------------------------------------------
By Himika Varma on Wednesday, June 2, 2004 - 04:15 pm:
Thanks guys. Have downloaded the methods and am working on them.
Will let you know if run into trouble again.
Regards.