Correction Factors of related substances
Posted: Sun Aug 26, 2012 11:50 am
Hello everyone,
i am new in this forum so please excuse me if i make no sense!
to get straigth to the point, we have a dilemma as far as the calculation of correction factor of the related substances of Ranitidine HCl is concerned. Our final product is expressed as % Ranitidine (as base) but our working std is Ranitidine HCl. When calculating the % of the related substance we take into consideration the convertion of Ranitidine HCl to Ranitidine (base) but our problem is ...do we have to make this convertion when we calculate the correction factor of each related substance? I tried to make my point clear, i hope i did. If there is anyone that can help me please answer!
Thank you in advance
i am new in this forum so please excuse me if i make no sense!
to get straigth to the point, we have a dilemma as far as the calculation of correction factor of the related substances of Ranitidine HCl is concerned. Our final product is expressed as % Ranitidine (as base) but our working std is Ranitidine HCl. When calculating the % of the related substance we take into consideration the convertion of Ranitidine HCl to Ranitidine (base) but our problem is ...do we have to make this convertion when we calculate the correction factor of each related substance? I tried to make my point clear, i hope i did. If there is anyone that can help me please answer!
Thank you in advance