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Ice-cold acetonitrile

Posted: Tue Jul 31, 2012 7:12 am
by dr_Pyrex
In some sample prep protocols (mainly plasma samples) I have found information about adding "ice-cold acetonitrile". Could you explain reason for it?

Re: Ice-cold acetonitrile

Posted: Tue Jul 31, 2012 6:41 pm
by Don Shelly
I'm told that the temperature aids in protein precipitation