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- Posts: 2
- Joined: Thu Jul 12, 2012 4:22 pm
Hi,
I am currently setting up the Organotin method using the ISO method. However, I have come across many problems with the extractions of the tins. Currently the samples we are analysing contain significant amounts of hydrocarbons and it is causing huge interference for the GCMS (SIM) to handle and accurate quantify the compounds. The method recommends clean-up with silca/alumminum oxide but this has not reduced the interference enough. Due to the sensitivity issues of the method, dilutions would be cause significant problems with attaining the LOD. Further clean-ups involve the use of Silca/Silver nitrate but I am having my doubts whether this will successfully remove the background. I am looking for a viable solution to remove the organic interference without affecting the recovery of the organotins.
Any suggestions would be much appreciated?
Many thanks in advance.
I am currently setting up the Organotin method using the ISO method. However, I have come across many problems with the extractions of the tins. Currently the samples we are analysing contain significant amounts of hydrocarbons and it is causing huge interference for the GCMS (SIM) to handle and accurate quantify the compounds. The method recommends clean-up with silca/alumminum oxide but this has not reduced the interference enough. Due to the sensitivity issues of the method, dilutions would be cause significant problems with attaining the LOD. Further clean-ups involve the use of Silca/Silver nitrate but I am having my doubts whether this will successfully remove the background. I am looking for a viable solution to remove the organic interference without affecting the recovery of the organotins.
Any suggestions would be much appreciated?
Many thanks in advance.
