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PFPA and BSTFA

http://www.chromforum.org/viewtopic.php?t=20193

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PFPA and BSTFA

Posted: Fri Jun 29, 2012 8:02 pm
by adsfo
Is there any concern running PFPA and BSTFA derivatives on the same GC/MS (same column)? A while ago I read somewhere that there can be some cross reactivity between those two derivatizing agentns leading to rapid column degradation.

Re: PFPA and BSTFA

Posted: Fri Aug 24, 2012 1:37 am
by bird
The by-product of PFPA is an acid, and that is the main culprit for column degradation.

BSTFA is a much better choice for fused silica columns, as it can potentially aid in repairing it.
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