¿HPLC method for vitamin D3 dissolution in tablets?
Posted: Thu May 31, 2012 6:54 am
Hi everybody!
We need to develope a HPLC method for the determination of vitamin D3 in the dissolution test for alendronic acid/cholecalciferol tablets (70mg/2800 UI). The FDA mentions the conditions for the dissolution test for both actives. In the case of cholecalciferol the medium is 0,3% SDS in water and the volumen is 500 mL. Does anybody know about an uv HPLC method for this type of assay?
Thank you very much in advance!
We need to develope a HPLC method for the determination of vitamin D3 in the dissolution test for alendronic acid/cholecalciferol tablets (70mg/2800 UI). The FDA mentions the conditions for the dissolution test for both actives. In the case of cholecalciferol the medium is 0,3% SDS in water and the volumen is 500 mL. Does anybody know about an uv HPLC method for this type of assay?
Thank you very much in advance!