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LC-MS low mass cutoff

Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.

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LC-MS low mass cutoff

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fandaga
Does anyone know of an LC-MS instrument that has a low mass cutoff below 18? I have a molecule that has significant in-source fragmentation into what I'm assuming is an ammonium cation, but I can't see this ion on my current MS instruments due to very little ion transmission below 50. I have Agilent (1100 MSD, 6140 MSD, and LC/MSD TOF) and Waters (Quattro Ultima) instruments. Or is there a way to increase the transmission of low mass ions on my current instruments?

Thanks a lot,
-Ryan

Re: LC-MS low mass cutoff

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Klaus I.
Good luck!
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