polar and unpolar compounds

[stelef]

Do you know any column that can be used for both very polar and unpolar compounds in the same injection?

[danko]

Hi stelef,

Go for a polar embedded stationary phase. You’ll have to choose a vendor yourself. Almost all manufacturers have these columns in their portfolio.

Best Regards

[Vlad Orlovsky]

Mixed-mode was designed to do that. Just see the discussion on Method development time limits here.