Minimum k’
Posted: Mon May 09, 2005 6:20 pm
Hi, I’m developing my first HPLC Method and I can’t seem to find any information on what is generally accepted as a minimum k’ for any given peak of interest. Any thoughts?
pharmaceutical regulatory agencies *suggest* (but do not require) that any measured peak should have k' > 2.
Generally recommended ideal range is 2-10
At the extreme, 1-20