validation of GC standard mixtures
Posted: Wed May 04, 2005 4:57 pm
I am currently in the process of validating our GC procedure. I have never done this before, nor is there a written SOP on it. And if it has been done by my company before, there are no notes that I can find anywhere. I know what parameters need to be investigated, but I don't know what limits are acceptable for different criteria. Specifically and right now, I am trying to show that the compounds in our standard mixtures are not significantly different (in area and retention time) than when they are when injected for ECD analysis individually. How do folks determine limits for % error, %RSD, or % relative difference, on comparisons like this? I can calculate them...I just don't know if the numbers I come back with are acceptable or not.