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Eudragit and ethyl cellulose - HPLC assay

Posted: Tue Jan 03, 2012 9:13 am
by bookoon
Hi Folks

Have any of you worked on HPLC analysis (assay) of Eudragit LD30 (Methacrylic Acid - Ethyl Acrylate Copolymer (1 is to 1) Dispersion 30 per cent) and Ethyl Cellulose?

Re: Eudragit and ethyl cellulose - HPLC assay

Posted: Tue Jan 03, 2012 11:52 am
by unmgvar
in polymers it is important to know the range of the expected sizes of your compounds.
are they water soluble or organic soluble?

Re: Eudragit and ethyl cellulose - HPLC assay

Posted: Tue Jan 03, 2012 1:35 pm
by Gerhard Kratz
You can do it with a SEC column, based on Polymer matrix, for water soluble compounds. A 50mmol/l acetate buffer pH5,8 I would use. Please google for more applications published on the www. Good luck.