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MS/MS for forensic

Posted: Fri Nov 18, 2011 10:02 pm
by jvjkorn
Hello, could anyone recomend me the best of most fitted MS/MS (rather GCMS or LCMS) covination for forensic science analysis. I will do toxicology, drugs, alkaloids, pesticides. if you can reffer me to application notes

Re: MS/MS for forensic

Posted: Sat Nov 19, 2011 3:35 am
by Jetjamnong
Hello, jvjkorn
I work drugs analysis with LC-QTOF for wide ranges of drugs successfully and I very thanks to Marjo Kolmonen, Antti Leinonen, Anna Pelander, Ilkka Ojanpera (University of Helsinki) for their exellent work and valuable scientific paper (In scope of doping control analysis) as I applied to my work (Clinical and Forensic Toxicology analysis). You can find many many excellent papers from several expert as the following.
1. A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-of-flight mass spectrometry. (Marjo Kolmonen, Antti Leinonen, Anna Pelander, Ilkka Ojanperä,. Helsin Finland)

2. Fast analysis of doping agents in urine by ultra-high-pressure liquid chromatography–quadrupole time-of-flight mass spectrometry (F. Badouda, E. Grataa, L. Perrenouda, L. Avoisa, M. Saugy, S. Rudazb, J.-L. Veutheyb,.Switzerland)

3. Multi-analyte procedures for screening for and quantification of drugs in blood, plasma, or serum by liquid chromatography-single stage or tandem mass spectrometry (LC-MS or LC-MS/MS) relevant to clinical and forensic toxicology (Prof. Hans H. Maurer,.University of Saarland, Homburg (Saar), Germany)

4. Drugs of abuse screening in urine as part of a metabolite-based LC-MSn screening concept (Dirk K. Wissenbach & Markus R. Meyer & Daniela Remane & Anika A. Philipp & Armin A. Weber & Hans H. Maurer)

5. Development of the first metabolite-based LC-MSn urine drug screening procedure-exemplified for antidepressants (Dirk K. Wissenbach & Markus R. Meyer & Daniela Remane & Armin A. Weber & Hans H. Maurer)

6. A multi-target screening analysis in human plasma using fast liquidchromatography–hybrid tandem mass spectrometry (Part I to Part II) (V. Viette, D. Guillarme, R. Mylonas, Y. Mauron, M. Fathi, S. Rudaz, D. Hochstrasser, J.-L.Veuthey,.Switzerland)

and some idea I learned from AIT Lab websit :
http://www.aitlabs.com/expert-research.aspx

Best Wishes
Jetjamnong