Chromatography Forum

I will buy GC MS, but still confusing which one that better between Agilent and Bruker.

i work in oil and fat manufacturing so That GC-MS will be used for analizing FAME, DAG and TAG.

Thanks

Get a sample run on both, make sure you are comparing like for like (Agilent 250l/s turbo to Bruker 350l/s)
Check local service and support. Compare the software for ease of use etc. Then take into account price and buy the one that's best.
Simples

Interesting way of making a comparison....Big pumps doesn't make a very good comparison and price definitely has nothing to do with instrument performance. Check to see which of the instruments gives you better sensitivity, (ask them to run a sample for you), which might not be that important if you are not doing low level work, but do check out the software and support/service of the instruments locally. You might want to check to see if any of your collegues have an instrument and see what they say, also I am sure there's groups of people in your industry and they might have an opinion. Price should never be the deciding factor if there's a budget for an instrument.

I have worked with many Agilent instruments in the past and I have loved working with each one. They are a simple and easy to use design while being very rugged and sensitive (for most applications). They are also relatively low in cost compared to others. One drawback may be a small lack in sensitivity or mass resolution power versus other vendors. However, if you only intend on using it for unit-mass resolution (around 0.5 amu peak width) experiments and the factory sensitivity is more than enough for your needs then I would say the 7890/5975 is a great system for you. If you want to be able to "push the limits" of an instrument and maybe get higher mass resolution or higher sensitivity for other experiments it might be difficult with the stock Agilent instrument. Although, they do offer an "Extended Linearity/High Sensitivity" Ion Draw out Plate which has given me pretty good results for PCBs (calibration range is 0.5 ng/mL to 2000 ng/mL @ 1µL injection for most PCB congeners).

In general, Agilent makes a very robust instrument but they are limited in some ways. I have never used a Bruker GC-MS before and I have no idea about the specs on them. I know the Thermo single quad instruments offer slightly higher sensitivity and mass resolution capability than the Agilent systems but I know they require a lot more maintenance on the Ion Optics to keep it running optimally. May be the same story with the Bruker.

follow on from ceinstruments, if you require reproducable data then i would suggest that you get an rsd over much higher injecjetion count,rather than one, which is tuned for the best performance. if your sample is "tricky" I would ask the vendor to give you a complete sequence of injections of the same standard to confirm the instrument performance over time

We are solely an Agilent lab and have platforms starting with a 5890/5971 and migrating to our latest instrument, a 7890/5975Inert. All of the instruments work great and we are routinely analyzing compounds in the low ppb to high ppt range. The only drawback that I have with the Agilent systems is the MSD Productivity Chemstation. We have specific needs concerning calibration and presentation of the data. If you want to effectively report data using the extracted ions, you will need to learn how to write macros to easily accomplish this task.