TMS derivatives mass spectral data base for GC/MS?

[Sajan]

I am new to GC/MS. Looking for TMS derivatives mass spectral data base for GC/MS. Specifically require identification of compounds based on ions (mass spectra). Can anyone please provide me the weblink to database or provide some useful guidance.
Thanks, George

[Jetjamnong]

No specific EI-GC/MS TMS libraries are available, but some compounds in NIST library are available in TMS and other derivatisation form (TMS, PFP, etc.). If you finding mass spectral library for drugs and toxic substances, I think PMW mass spectral library can be use in some of TMS as well as NIST. In my opinion TMS mass spectra is difficult to identify becuase it major fragment is TMS group (73) and not specific like as water neutral loss.
What the compounds are you looking for? is it necessary to use specific TMS library.

Jetjamnong

[Don_Hilton]

It depends on what kinds of compunds you are looking for. MPW has a nice library of spectra that are related to toxic compunds, drug metabolites, and some similar classes. There is a library at teh Max Plank web site that has plant metabolites. Some are identifed compunds others are for reference to match compunds up when seen again. Last time I went looking for it, it took me a while - but I would suspect that it can still be found. NIST has some TMS derivatives as does the Wiley library. There are some other small libraries that you can find on searching the internet. I believe that I recall a toxic comounds library from a lab in Canada and library with steroid or lipid compounds - but it has been at least 5 years since I was looking for such libraries.

I would suggest:
1) tell what kinds of compunds and someone who knows of a related specialty library may jump in and help you out
2) do some digging on the internet.
3) consider building your own library. You would not be the first. I am aware of a number of libraries that corporations have built up over the years.

[Consumer Products Guy]

consider building your own library. You would not be the first. I am aware of a number of libraries that corporations have built up over the years.

That's what we did (we also have NIST). Ours is proprietary.