ICP MS and GCMS, LCMS..IS THERE A BIG DIFFERENCE

[seamoro]

HEY...JUST WONDERING IS THERE A BIG OPERATIONAL DIFFERENCE BETWEEN ICPMS AND THE OTHER MS LIKE GC AND LCMS?

[MaryCarson]

I would say there is a significant difference. Probably depends on how you define "big."

[Zuhairdi]

When, u said MS, u r referring to one term MASS SPECTROMETER (that is a detector)..
but if u said GC-MS u r refering to the GAS CHROMATOGRAPHY (analytical instrument) WITH MASS SPECTROMETER (detector)..

When u change the word to ICP-MS.. it does mean Induced Coupled Plasma (analytical instrument) with Mass Spectrometer (detector)..

So, the different is the type of analytical instrument... the only same thing they have is the detector (MS)..

[krickos]

mm

Well for ICP-MS trace analysis you will need a clean room to operate in, requirements could look like this:

- Indoors (really )
- Free of smoke, dust and corrosive fumes
- Not prone to excessive vibration
- Out of direct sunlight
- Away from heat radiators
In order to minimize contamination problems, a
dust-free environment is necessary. For ultra-trace
techniques, environmental contamination becomes a
limiting factor in the analysis. To quantitate ubiquitous
elements such as Fe, Ca, K, Na, etc. below 1 ppb (μg/L),
a class 1000 environment is necessary for sample
preparation and analysis. This is not an indication of
the performance limitations of the instrument, but
a recommendation for an ultra-clean environment.