Method validation, precision and Accuracy
Posted: Fri Sep 30, 2011 4:21 pm
Hi I'm just wondering what everyone does for intermediate precision, specifically what statistical analysis do you perform on the data from 2 labs on the same sample?
My other question is; what are the guidelines for recovery? I've read that recovery specifications should depends on the concentration of the analyte, but am having a hard time matching this up to any regulations, which would help me greatly.
I've performed accuracy and range 3 different ways on my method and always get a recovery of 95% (woohoo consistent) across all levels. My active is 0.23%.
My other question is; what are the guidelines for recovery? I've read that recovery specifications should depends on the concentration of the analyte, but am having a hard time matching this up to any regulations, which would help me greatly.
I've performed accuracy and range 3 different ways on my method and always get a recovery of 95% (woohoo consistent) across all levels. My active is 0.23%.