Chromatography Forum

Hi,

Could someone please help me out, how do I determine the conversion and selectivity of a reaction from Gas Chromatograms?

Greatly appreciate your help!

Some info would be good. Would you be the analyst or the synthetic chemist?

hmm...both...i'm carrying out the reaction and afterwhich analysing the conversion and selectivity via GC?

Hmm you don't seem able to follow directions very well.

I expect the worst.

Rod

Hmm you don't seem able to follow directions very well.

I expect the worst.

Rod

And better Post Titles will get you more "looks" here, your post title is terrifically poor.

To get to the question of the post. You are asking how to to a quantitiative technique. That covers a lot of territory. Briefly, you need to obtain GC conditions that will separate your starting compund and reaction products of interst. You need to be able to detect them in a way that you can obtain quantitiative information. If you have samples of pure compounds, you can establish quantititation. If not, you may only be able to obtain a rough estimate of what is going on. Worst case, you ratio everyting against one chromatographic peak and declare that one sample has more or less of a compund than some other sample - relative to the first compund.

So, do you you known how to set up a GC and establish a separation? Do you know how to use the software for quantification? Do you have pure materials for making standards?

It is all details. As open ended as the question has been left, it asks for the skill set and time that is the pay check for some of us who read these posts. The more details you can give, the more focused an answer can be.

Have you got an analyst that can help you? I'm afraid to try to give a set of instructions on here would take a few years, these are complex instruments with a million settings.