expert knowledge of HPLC and GCMS = GOOD AT LCMS

[seamoro]

HEY,I have excellant knowledge of HPLC and GCMS but not much experience of LCMS. With having good knowledge of HPL and GCMS make LCMS easy for me?

[lmh]

probably, but only if you have an open mind (which you probably do). If you can learn what you've already learned, you should have no problem in learning LC-MS, but do remember that the mechanism of ionisation, the ions formed, and the fragmentations they undergo, are completely and utterly different to GC-MS.