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Pesticides residus
Posted: Sun Jul 24, 2011 2:48 pm
by mabrouk
I work in laboratory of analysis of the residues pesticides in the agricultural produce,
We will buy a UHPLC/MSMS triples quaderipôle for the application of the QuECheRS method in order to reach limits of quantification of 10 ppb.
With LC MSMS 8030 (with Nexera), is it possible to reach this limit (10 ppb)?
Therefore the instrument is robust or not?
Re: Pesticides residus
Posted: Thu Jul 28, 2011 1:01 pm
by yangz00g
The answer is yes for many compounds, no for some difficult ones (e.g., pyrehroids), but it all depends on the pre-concentration factor of your sample and the sensitivity of the instrument (e.g., less sensitive, more concentrating, more sensitive, less concentrating).
Just remember, no single instrument can measure all pesticides with desirable performance.
Re: Pesticides residus
Posted: Mon Sep 05, 2011 9:25 am
by Alexandre
Dear Mabrouk,
If you have doubts regarding performance of your MS, ask Shimadzu for performance verification compound, procedure and criteria. Usually your local Shimadzu engineer gladly helps or sometime even will perform this test for you. Check that instrument passes the test, this test was also performed at commissioning of the instrument. If you do not have this record, Shimadzu should. After you are confident in your instrument, build up evaluation further, try SS using well published analytes, if you use ES+, atrazins are a good mixture. Proceed to ppm level injection to check if you have a signal, then move to your range. 10 ppb is a problem for many pesticides, you need to concentrate. If analytes can not be ionized it is a problem too.
Alexandre.