sodium acetate determination

[bfranc81]

Hi everyone!
I'm looking for one method to determine a possible sodium acetate impurity in my sample. It's just an option, we are not sure of this impurity.
To analyze my sample, I'm working with a Symmetry C8, ammonium acetate buffer pH=3 and a mixture acetonitrile/methanol as organic solvent. Wavelength is dual: 220 and 254nm.

Is there any option to detect sodium acetate with these conditions?

Thanks!!!

B.

[tom jupille]

No. You will need a totally different method.

[bfranc81]

And, how can I start?? Could it be better with GC??

[tom jupille]

If there is no other source of sodium in your sample, it might be easiest to analyze that (ion-selective electrode? ion chromatography?). If there are no other major anions, then spe followed by ion chromatography or spe followed by GC?

[Bintang]

Sodium is easily determined by atom absorbtion spectrscopy (graphite furnace or flame) or ICP.
For acetate there are numerous HPLC applications online.