Chromatography Forum

attention GPC gurus out there. I am looking to buy a column to determine MW of a polyester (poly-3-hydroxybutyric acid)
and am looking for a GPC column to use. I believe my polymer is ~500,000 MW. It will dissolve in chloroform
and I have Mark-Houwink constants for my polymer in chloroform and for my PS standards in chloroform.

I would also like to run in hexafluoroisopropanol so I can use my UV for a detector.

Any suggestions on a good column?

Macromolecules Vol.: 33 No.: p:6595 - 6601 ( 2000 )
Title: Theoretical Prediction of Molecular Weight on Autocatalytic Random Hydrolysis of Aliphatic Polyesters
Author: Haruo Nishida, Mitsuhiro Yamashita, Masumi Nagashima, Norikazu Hattori, Takeshi Endo, and Yutaka Tokiwa

Group1: Synthetic polymers

J. Appl. Polym. Sci. Vol.: 70 No.: p:2259 - 2268 ( 1998 )
Title: Blends of Aliphatic Polyesters. 3. Biodegradation of Solution-Cast Blends from Poly(L-lactide) and Poly(epsilon-caprolactone)
Author: H. Tsuji, A. Mizuno and Y. Ikada

Maybe these two publications will give you an idea about GPC columns suitable for your application.
Good luck