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Separation by GC

Posted: Wed Mar 16, 2005 2:47 pm
by kumaresan
Which column is good for the seperation of IPA and acetone

Posted: Wed Mar 16, 2005 4:09 pm
by DR
If you have a good programmable oven and a cold injector port, you could probably do that w/ any packed column (or empty tubing).

Acetone Isopropanol

Posted: Wed Mar 16, 2005 4:38 pm
by chromatographer1
Moderate to very polar columns will do the best job on this separation, whether packed or capillary.

Carbowax to a less polar 1701 will separate these two analytes.

There is an amazingly close elution on methyl silicone and porous polymers, isn't there?

best wishes,

Rod

Posted: Wed Mar 16, 2005 4:45 pm
by WK
Do not use a 624 since they nearly co-elute or only just resolve (even though its good for solvents generally).
WK

1301?

Posted: Wed Mar 16, 2005 8:33 pm
by chromatographer1
That is correct, a 3% cyanopropyl 3% Phenyl methyl silicone (624 aka 1301) is less polar than the 1701 (7% cyanopropyl 7% phenyl methyl silicone), but anything more polar should be fine for the separation of acetone and isopropanol.

Posted: Wed Mar 16, 2005 10:13 pm
by Ron
You might also want to consider using a PLOT column. I got some very good separations of polar solvents on a PLOT-Q column a few years back, although I don't remember if your two analytes were in the mix.

column for ipa acetone

Posted: Fri Mar 18, 2005 7:39 pm
by jtoxx
I have seen haysep s , carbowax , poropak work also several cap columns such as RTX BAC1, RTX BAC 2, and RTX 200.

Posted: Mon Mar 21, 2005 10:54 am
by MikeD
My records show (approx) Kovat indices:
on non-polar silicone - acetone 487, isopropanol 488
on OV1701 equivalent - acetone 589, isopropanol 601.
These were measured with temperature programming so the correspondence with the literature won't be too good, but it's an indication.

Acetone IPA separation

Posted: Mon Mar 21, 2005 12:02 pm
by chromatographer1
Supelco's Equity 1701 will separate acetone and IPA at 40°C very cleanly, even when dissolved into water. More polar columns should also separate these two analytes.