Pyrolysis GC or LC/MS
Posted: Tue May 17, 2011 2:48 pm
Chlorinated hydrocarbons in soil can be analyzed by pyrolysis GC or by LC-MS. Why is pyrolysis GC preferred?
Help me, plzzzzz
Help me, plzzzzz
Here is my teacher's hints, don't know what to do. >:( >:(
Rather than answer the question for you, let me ask some questions that will lead you to the answer.
What is the boiling point of 2,4-D and related compounds?
What is the solubility of 2,4-D and related compounds in common solvents?
How polar is 2,4-D? Is it a compound that would work well on normal phase LC? Reverse-phase LC?
If you can vaporize 2,4-D, what would a good GC column be? At what temperature would it run?
What interferents would pyrolysis eliminate? What interferents would be unaffected? Which would be enhanced?
What interferents would solvent extraction eliminate? What interferents would be unaffected? Which would be enhanced?
What detector would be best for the molecule in each system? What is the likely detection limit? What about selectivity?
Now, given the totality of the evidence, what are the chemical and physical reasons for choosing one method over the other?