Sensitivity problem with halogenated pesticides
Posted: Thu May 12, 2011 1:21 pm
I'm running two GC-MSMS systems from Waters (with Agilent GC and Gerstel PTV inj.). The oldest of them have had problems with sensitivity fore a long time now, and it is mainly the halogenated pesticides that is'nt sensitive enough. I've had engineers from Waters here that have changed the detector and one of the quads, cleaned the source and changed the column, but nothing seems to work. The other instrument are running perfectly with the same method and instrument parameters.
Now I'm thinking the problem is in the GC rather than in the MSMS. I wonder if there can be an active site in the PTV injector or somewhere else in the system that have this effect on halogenated compounds? Is there anything else I can try?
Now I'm thinking the problem is in the GC rather than in the MSMS. I wonder if there can be an active site in the PTV injector or somewhere else in the system that have this effect on halogenated compounds? Is there anything else I can try?