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LC-ESI MS of sugar alcohols

Posted: Fri Mar 11, 2005 7:22 pm
by FastLC
Any familiarization out there using LC-ESI MS for sugar alcohols or polyols.

Thanks.

APCI

Posted: Tue Mar 15, 2005 4:42 pm
by Noser222
APCI might be the way to go for you. I have used an amino column with a mobile phase of about 85% Acetonitrile (+ 1.2% CHCl3) 15% Water. You detect M+Cl- in the negative mode. It is similar to this method:

http://www.chem.agilent.com/scripts/Lit ... WHID=25414