reg N hexane limit

[chrom]

This is regarding limit for n-hexane. Our practice is to put specification of n hexane includes with its fractions. (2 Methylpentane,3 Methylpentane, Methylcyclopentane and n-Hexane) . The limit we follows 290ppm. And for Cyclohexane its 3880ppm. Should we follow this or any other startegy we need to adopt.

Thanks for Valuable inputs.

[EUROFINS]

Have a look at http://www.bsa-site.nl/ems/nl/downloads_macwaarden.html

[DSP007]

This is regarding limit for n-hexane. Our practice is to put specification of n hexane includes with its fractions. (2 Methylpentane,3 Methylpentane, Methylcyclopentane and n-Hexane) . The limit we follows 290ppm. And for Cyclohexane its 3880ppm. Should we follow this or any other startegy we need to adopt.

Thanks for Valuable inputs.

http://www.ema.europa.eu/docs/en_GB/doc ... 002674.pdf
its LOW.

Of course, I would like to know "what grass was smoking mathematician", who was calculate dose of hexane .
However this small mistake.

When these recommendations are translated on the Russian Pharmacopoeia 2008 (XII) - was thrown out a way to calculate the NOEL .
A section relating to the third group is formulated so , that now we must determined ethanol in drug substances. Although its in the beer to a billion times more. And it $@&# also became law. Bureaucratic war on this issue has been going on for three years . These translators are obviously "smoked marijuana".