Best column to separate bromo and chloro analogs?
Posted: Tue Mar 29, 2011 7:57 pm
What type of column would be best to separate bromo and chloro analogs of a MW ~500 drug?
For example, these two:
For example, these two:
Interesting....
First one I might try would be a perfluorophenyl, perhaps with some TFA in the mobile phase.