Chromatography Forum

Are these pumps (1100 vs 1200) truly identical? That is, the 1312A vs 1312B? Not the 1260 that is truly a different beast.

Yes, the 1100 and 1200-series Binary pumps are the same (same identical Agilent internal P/N's. Any real differences are due to the exact year of build which may have incorporated different main board upgrades and/or firmware changes, but not much else). *The 1260 is just a 600 bar pressure rated version of the same pump.

From what I have seen the G1312B is binary SL pump, i.e. 600bar max. The SL version also separates the pressure sensor from the pulse dampener which allows one to bypass the pulse dampener to reduce gradient delay. The G1312A has a max pressure of 400bar and the pressure sensor is part of the pulse dampener. I believe the 1260 is just a relabled 1200SL but dont have any "proof" of this. the specs appear to be the same. not sure why but Agilent discontinued the 1200 replacing it with the 1260 line.

OK, I goofed (I only read the top portion, Are Agilent 1200 and 1100's the same) and there is a lot of confusion about the different versions of Agilent's (HP) HPLC modules. This is in part due to the fact that Agilent re-uses the same module part number for many items as a product goes through various updates, but "updates" the description of it only in their system. Confused ? You should be.

In this example, the Binary pump started off with a front label of 1100-Series and has inherited different front panels labels (1100, 1200 and 1260), main boards, mixers and firmware upgrades over the course of many years. The suffix change option from A to 'B' DID emphasize an upgrade to the 600-bar head several years ago. This occurred while the 1100 label was still being used. When they replaced all of the front panels on the 1100's with ones that now said "1200" (a marketing move), the modules remained unchanged. They module's description was simply edited to show "1200" instead of 1100. Same part numbers for everything. Later on, they changed all of the 1200-series B (or SL) versions to the new '1260' label (all 1260's are 600-bar versions to distinguish them from 1220's which are 400-bar). They are basically all the same unit, but do have some small differences in firmware, plumbing and compatibility with other controllers (and software). The main difference is that the front panel labels are different. Now, the part that drives us all nuts is that the G1312A SL and/or G1312B have three different product descriptions by Agilent (1100 Binary SL, 1200 Binary, 1260 Binary), but are basically the same system. The year they were manufactured determined which label they received. Today, if you order a Binary pump in a 600-bar version, then it will have the part number G1312B too (which is described as a 1260 Binary Pump).

If you are shopping for a Binary pump, only the pressure spec and controller compatibility are issues. Just make sure you purchase the version that will work with your other modules and software. They are all great pumps.

Thanks, I have all versions of the binary pumps, the G1312A's in both 1100 and 1200 versions. Based on the serial numbers, the 1100 binaries were made in the US, while the 1200s were made in Germany. The 1312Bs are as you say "1260" pumps, rated to 600 bar. There is some extra plumbing in them, some extra

firmware that compensates not only for solvent compressibility like the 1312A but also the pump "elasticity", that is, the deformation of the individual pump's components at high pressures. Then the 1290 is the 1000 bar pump, a totally different animal, for UPLC. The reason I asked about a difference is based on performance difference I'm getting from the old 1100 to the new 1200 G1312A. Otherwise the pumps appear identical in every way: parts, firmware, design, etc. And the US vs DE serial numbers.

Hi All,
Based on the serial numbers, the 1100 binaries were made in the US, while the 1200s were made in Germany.

basically you can ask to have 1200 made in US because they have manufacture in US too (they have manufacture for analytical instrument in US, Germany, Japan, China and singapore).

The reason I asked about a difference is based on performance difference I'm getting from the old 1100 to the new 1200 G1312A. Otherwise the pumps appear identical in every way: parts, firmware, design, etc

Could you describe what is diffrence in prefromace between these pump?

Hi All,
Could you describe what is diffrence in prefromace between these pump?

Perhaps the difference you are seeing is due to the difference in compressibility corrections available on 1200 binary pumps vs 1100? Are you using the same compressibility setting on both pumps?

Please describe the performance differences you're seeing.