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LC-MS analysis of Al standard

Posted: Tue Feb 22, 2011 1:06 pm
by BoGa
Hey all

I have a general problem regarding the use of a RP C-18 column.

When i try to analyse a standard solution of Aluminium i do not get any signal at the ICP-MS (ELAN 6000) when i use the RP column.

If i remove the column and inject the same volume and concentration of aluminium standard solution i get a clear peak.

Do anyone have an idea to why i dont get a signal for aluminium when i use the RP column. It should pass right throug the column without any retention?

Re: LC-MS analysis of Al standard

Posted: Wed Feb 23, 2011 8:08 am
by BoGa
I've figured out that it is probably due to complexation of Al ions with the silica material.