Chromatography Forum

How to Calculate Peak Gaussian Factor using Agilent GC CHEMSTATION or MSD CHEMSTATION

1.EPA METHOD 531.1 PAGE 22
2.EPA METHOD 552.2 PAGE 32
3.EPA METHOD 508.1 PAGE 24

All the above EPA Methods needs to perform this.Is any body can share your thoughts.

I used Chemstation and Enviroquant Chemstation for EPA methods calling for Peak Gaussian Factor and never found a calculation built in for it. It is a different calculation that any of the USP ones. I did it the pen-and-paper way: zoom in on the particular peak with baseline, print it, and get out my ruler and triangle to draw it by hand. There might be a work-around, but I never did find it.

Peak resolution and USP tailing can be found in the Extended Performance Report. I used USP tailing to judge day to day performance, but then did Peak Gaussian Factor to comply with the method.