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what is this phenomenon called

http://www.chromforum.org/viewtopic.php?t=15563

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what is this phenomenon called

Posted: Mon Jan 24, 2011 8:08 pm
by moonchips
Greetings,

For HPLC mesurement, when we use a too strong organic solvent as the sample diluent, eg. 100% IPA, 100% NMP, THF etc., we can have distorted peak shape, either extremely bad tailing or very weird hump before the main peak. Is there a term to describe this phenomenon?

Thanks,

Re: what is this phenomenon called

Posted: Mon Jan 24, 2011 8:44 pm
by tom jupille
There is no "official" term. I usually just call it the "strong diluent effect" or "strong solvent effect". :wink:
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