Chromatography Forum

sir.i am doing some work by degradation studues of api.my parent molecular mass was 349.but by degradtion in sodium hydroxide 0.1 N i got one of my degration molecule mass is 380 please tell me the answer.
thanking you
vinay

sir.i am doing some work by degradation studues of api.my parent molecular mass was 349.but by degradtion in sodium hydroxide 0.1 N i got one of my degration molecule mass is 380 please tell me the answer.
thanking you
vinay

(apologies for replying in "hijacked" thread)
perhaps 380 is due to a dimer, cluster or adduct ion of the degradant. It's hard to tell without the synthetic scheme

hi vinay
it is very difficult to predictb fom the data u have provided
but it can not be a dimer or anythnig else
as the mol wt change is very small to acoount for such a formasation
ok
and i dont know and how can mol wt in cerase of a degradation pdt
do u have any report in lit. of such an incerase i do not think so
thank you
aniket