HPLC Column selection for an acid sensitive analyte

[jeegar]

I am looking to buy a C18 column, 15 cm, 5 um dp and 4-4.6 id, for my reversed phase HPLC application. The analyte is acid sensitive, therefore, I should work with a mobile phase with a pH of about 8. I was wondering what column I should use to tolerate the alkaline pH range and yet not expensive.

I would certainly appreciate your help.

Sincerely,
Jeegar

[tom jupille]

Many manufacturers now have columns stable at pH 8. This is not an inclusive list, but:

Waters Xterra
Phenomenex Luna
Agilent Eclipse

come to mind

[Kostas Petritis]

Agilent Extend and Phenomenex Gemini to name some more...

[jeegar]

Dear Tom and Kostas,

Thank you for your response. I will look into them.

Jeegar