Software to scale up HPLC method

[joshisushil15]

How can i get the software (Free) for scaleup of analytical HPLC method to prep HPLC. or calculation involved
PLease advice .

[danko]

You don't need a software for that. It takes shorter time to figure it out utilizing a simple pocket calculator than booting a PC.
You might like to describe the case here and I'm sure you'll get a lot of responses.

Best regards

[Gaetan Glauser]

As Danko said, calculation for geometrical transfer of HPLC conditions is really simple, however if you really wish to use a soft, check this out:

http://www.unige.ch/sciences/pharm/fana ... gement.htm

[joshisushil15]

As Danko said, calculation for geometrical transfer of HPLC conditions is really simple, however if you really wish to use a soft, check this out:

http://www.unige.ch/sciences/pharm/fana ... gement.htm

Thanks for the response n the link.
Actually, I want to isolate the N-formyl deacetyl thiocolchicoside from the API thiocolchicoside by prep HPLC.
please suggest in this regard

thanks in advance

[danko]

Now I understand you need a real intuitive software.
Or a mind reader
What happend to the upscaling job

Best Regards

[joshisushil15]

the resolution between these two compounds is very small in analytical method developed. I m not getting the proper resolution on upscaling.
Thatswhy i need the calculation/software for upscaling to prep and isolating the impurities.