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Problem with a diluent in a GC analysis
Posted: Sun Dec 05, 2010 4:47 pm
by chemistab
I try to determine some solvents (methanol, Ethanol, Ethyl Acetate, toluene and DMSO) by GC-FID. I use NMP as diluent. My problem is that the diluent gives a not stable peak at the same retention time with DMSO. I changed some parameters of GC (for example the temperature program to the oven) but the problem was not solved.
Any suggestion please?
Re: Problem with a diluent in a GC analysis
Posted: Sun Dec 05, 2010 6:23 pm
by chromatographer1
Two of the obvious come to mind.
Use a different Diluent.
Use a different column.
Don't insist on science working as YOU want it to work to your convenience.
Sometimes, we ourselves have to realize that on occasion, sometimes:
You eat bear.
The bear eats you.
In other words, you may require a second method to do DMSO analysis using methyl alcohol, or methyl acetate or methylene chloride or some other solvent as a diluent.
best wishes,
Rod
Re: Problem with a diluent in a GC analysis
Posted: Mon Dec 06, 2010 6:27 pm
by krickos
Hi
Well some litterature/catalouge searching would perhaps avoided the problem.
Column manufactures like Agilent/J&W typically has retetion indexes for DB-1, WAX and 624 columns for the most common solvents.