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RSD % of amino acid analysis (post column)

Posted: Mon Aug 30, 2010 7:22 am
by thohry
Hi all,

Anyone run post-column analysis of amino acid could please tell me what is the RSD% of the replicate results. That does not include sample prep.
Just roughly.

Thanks for any input.

Posted: Mon Aug 30, 2010 9:01 pm
by JGK
Based on Information from a multi-lab study we participacted in through the American Oil Chemist's Society (AOCS).

Labs using Post-column derivatization reported RSDs in the following ranges:

Intra-sequence (triplicate) 0 - 27% depending on residue and sample type.
Inter-sequence (n=6) 0 - 24% depending on residue and sample type.

Labs using Pre-column derivatization reported RSDs in the following ranges:

Intra-sequence (triplicate) 0 - 15% depending on residue and sample type.
Inter-sequence (n=6) 0 - 13% depending on residue and sample type.

Posted: Wed Sep 08, 2010 2:51 am
by thohry
Thanks for your reply.

In case, we use run standards, everything is fine, so what would the RSD expect to be. Anyone have run this kind of analysis?