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Wanted best and cheap system HPLC/MSMS
Posted: Wed Aug 25, 2010 1:59 pm
by faris
Hi every one. I am in process to buy HPLC + MS/MS. What would be the best combination in terms of price and performance. I am not talking about new equipment I am looking of for cheap and good
Posted: Mon Aug 30, 2010 8:08 pm
by mardexis
What about LCQ classic made by thermo fisher and Agilent1050
Posted: Mon Aug 30, 2010 8:37 pm
by faris
Wanted best and cheap system HPLC/MSMS
Posted: Mon Aug 30, 2010 9:25 pm
by faris
[Do you think Finnegan LCQ classic and Agilent 1050 would work ?]How about this? AB triple and 1100 wi CTC for $60Ks
http://www.labx.com/v2/adsearch/detail3 ... umb=420277[/quote]
Posted: Tue Aug 31, 2010 4:59 pm
by oscarBAL
Hi Faris; I do not know so much about LC/MSMS (at least so much as I would like...) but before go and could you please tell us what could be your application?
to say "Good HPLC MS/MS" it could be relative.
Thanks.
Posted: Tue Aug 31, 2010 5:08 pm
by mardexis
This last point is a good one. If you were setting up to do proteomics I would suggest the Thermo LCQ. If you are doing small molecule work I would go with the ABI system. I tend to favor Agilent for the HPLC mainly because I have more experience with it.
About my work nature
Posted: Tue Aug 31, 2010 7:22 pm
by faris
Hi guys, ad thank you for your replays. Mainly my work is involving small molecules pest side and carcinogens in food, I don't do that much protein analysis.
Posted: Wed Sep 01, 2010 6:10 pm
by oscarBAL
Hi Faris; probably I am not the qualified person; but I think you have to have in mind that if you are analyzing pest you will need sencitivity and apart of that high duty cycle and this means (if I remember well); can the instrument do all the changes in energy of collition, cone voltage, polarity, etc in a range of time that do not afect your sencitivity and your chromatography?
Remember is not the same when we have to analyze few compound that when we have to analyze 50 or more. if some day you want to use UPLC or go faster probaly you will not be able wtih this instrument.
I found some information in the internet you can check.
http://www3.appliedbiosystems.com/cms/g ... 040394.pdf
Personally think that there are better equipment but you will have to see if the API 2000 is enought for you; the other side is to have a good methodologies and sample prep, the instrument is only the 50%