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what is the best volatile buffer at neutral ph
Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.
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thanks a lot if you can give me any suggestion.
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- tom jupille
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I don't think there are any good volatile anions with pKa values near 7. On the cation side, if you can go up a bit (say, to the mid-7's) you would be on the ragged edge of the buffer range for ammonium, so something like ammonium formate or ammonium acetate might work.
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
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- Posts: 214
- Joined: Wed Dec 30, 2009 4:51 am
thanks a lot.
I don't think there are any good volatile anions with pKa values near 7. On the cation side, if you can go up a bit (say, to the mid-7's) you would be on the ragged edge of the buffer range for ammonium, so something like ammonium formate or ammonium acetate might work.
3 posts
Page 1 of 1
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