Shimadzu Nexera vs. Agilent 1290 vs. Waters aquity h

[janjena]

I just found the news on the internet about the new Shimadzu UHPLC System. The specification seems to exceed Agilent and waters data . Has anybody already some hands on experience on that system?

[Alex Buske]

Not even our Shimadzu service person.

Alex

[bisnettrj2]

It's probably too new to tell. Shimadzu is a littler fish in a pond dominated by Agilent and Waters, so entry into the UPLC market segment will be difficult. So far, there are no hard specs, and as Alex Buske said, not even his rep has seen one in action. The specs do seem to comp well with the 1290; and I have to say their "computer modeling of mixing process" graphic for their new low-volume mixer technology looks suspiciously like Agilent's JetWeaver mixer - perhaps there will be a patent infringement lawsuit in the future? Call Shimadzu and ask for a demo or a side by side specifications comparison against the 1290, the Acquity H-class, the Dionex RSLC, etc.

[Yves]

Waters has done a great job promoting high pressure and Agilent has tried to follow with high pressure and loop bypass to reduce delay volume. But both have not been able to rival in injection speed and eliminating carryover. The Nexera will have less than 0.0015% with no rinsing and will give better pumping precision and greater range of applications, 80% wider injection volume capacity and 80% wider range of pumping capacity than both of the above... All detectors will also provide 20% more data points, making this instrument a much more versatile tool for your applications... The LCMS-2020 is also much more sensitive and easy to service.

Shimadzu UFLC is in most LCMS labs and has also been used for the 2010 Vancouver Olympics.

Take a look at it if you have a chance.

Visit www.ssi.shimadzu.com

Regards,