GPC problem, help

[Dori]

I have a Styragel HR1 Column (THF). Methanol was used as eluyent by mistake for about 3 hours. Now I don't obtain good resolutions, probably the column is damaged.
Is it possible to fix it? Thanks.
Dory

[Uwe Neue]

If it does not perform any more after being converted back to THF, it is probably dead. Polymeric packings swell and shrink significantly as a function of the solvent. THF is a swelling solvent, methanol will shrink the packing.